Real Evidence: Red Wine Antioxidant Kills Cancer

RED WINES AND GRAPES KILLS CANCER!! 

Real Evidence Shows Red Wine and grapes are a powerful Antioxidant they Kills Cancer “Antioxidant research is very active and very seductive right now,” Okunieff said. “The challenge lies in finding the right concentration and how it works inside the cell. In this case, we’ve discovered an important part of that equation. Resveratrol seems to have a therapeutic gain by making tumor cells more sensitive to radiation and making normal tissue less sensitive.
” Resveratrol is known for its ability to protect plants from bacteria and fungi. Purified versions have been described in scientific journals as potential anti-cancer, anti-inflammatory and anti-atherogenic agents, and for their ability to modulate cell growth. Other well-known antioxidants derived from natural sources include caffeine, melatonin, flavonoids, polyphenols, and vitamins C and(E. A flurry of antioxidant studies in recent years has not proven how and why they work at the cellular level. Studying resveratrol as a tumor sensitizer. That’s when they discovered its link to the mitochondria.
The discovery is critical because, like the cell nucleus, the mitochondria contains its own DNA and has the ability to continuously supply the cell with energy when functioning properly. Stopping the energy flow theoretically stops the cancer. Researchers divided pancreatic cancer cells into two groups: cells treated without resveratrol, or with resveratrol, at a relatively high dose of 50 mg/ml, in combination with ionizing radiation. (The resveratrol concentration in red wine can be as high as 30 mg/ml, the study said, and higher doses are expected to be safe as long as a monitoring.)

They evaluated the mitochondria function of the cells treated with resveratrol, and also measured apoptosis (cell death), the level of reactive oxygen species in the cells, and how the cell membranes responded to the antioxidant.
 Laboratory experiments that resveratrol: -- Reduced the function of proteins in the pancreatic cancer cell membranes that are responsible for pumping chemotherapy out of the cell, making the cells chemo-sensitive. -- Triggered the production of reactive oxygen species (ROS), which are substances circulating in the human body that have been implicated in a number of diseases: when ROS is increased, cells burn out and die. -- Caused apoptosis, which is likely the result of increased ROS. -- Depolarized the mitochondrial membranes, which indicates a decrease in the cell’s potential to function. Radiation alone does not injure the mitochondrial membrane as much. 
The team also wanted to investigate why pancreatic cancer cells seem to be particularly resistant to chemotherapy. The pancreas, a gland located deep in the abdomen, produces insulin and regulates sugar, and pumps or channels powerful digestive enzymes into the duodenum. 
This natural pumping process, however, ends up ridding the needed chemotherapy from cells in the pancreas. But just as reseveratrol interferes with the cancer cells’ energy source, it also may decrease the power available to pump chemotherapy out of the cell. “While additional studies are needed,” Okunieff said, “this research indicates that resveratrol has a promising future as part of the treatment for cancer.”